The SMBG Study: Structured Self-monitoring of Blood Glucose in Non-insulin Treated Type 2 Diabetes

Download or read book The SMBG Study: Structured Self-monitoring of Blood Glucose in Non-insulin Treated Type 2 Diabetes written by Parsons Sharon and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The SMBG Study: Structured Self-Monitoring of Blood Glucose in Non-insulin Treated Type 2 DiabetesBackground: The benefit of Self-Monitoring of Blood Glucose (SMBG) in people with non-insulin treated type 2 diabetes (T2DM) continues to be debated with inconsistent evidence from randomised controlled trials and observational studies. There is a growing consensus that structured SMBG, whereby the person with diabetes and health care provider are educated to detect patterns of glycaemic abnormality and take appropriate action according to the blood glucose profiles, can prove beneficial in terms of glycaemic control and overall well-being.Aim: To determine whether structured SMBG with or without additional telecare support, can enable poorly controlled, non-insulin treated people with T2DM to better manage their diabetes.Method: A 12 month, multi-centre, randomised controlled trial was conducted in people with established (>1 year) T2DM not on insulin therapy, with poor glycaemic control (HbA1cu22657.5% u2264 13%). A total of 666 participants were recruited from 16 primary and secondary care sites across Wales and England. 446 people were randomised into one of three groups; Group 1 (G1), a control group receiving usual diabetes care; Group 2 (G2), carried out structured SMBG with clinical review every 3 months; Group 3 (G3), carried out structured SMBG with monthly telecare support from a trained study nurse. Participants in both SMBG groups (G2 & G3) and all healthcare professionals involved in the study received standardised training including SMBG technique, glycaemic pattern recognition and the use of the clinical algorithms. The testing regimen consisted of paired testing pre and 2 hours post breakfast and main meal, 2 days each week. This was increased to recording a 7 point profile for 3 days the week prior to the 3 monthly study visit. At each study visit clinical measurements, such as weight, waist circumference and BMI were recorded, and a blood sample taken to measure HbA1c and total cholesterol. Quality of life measures were also administered at each visit along with questionnaires to gauge attitudes towards SMBG. Blood glucose management was based on SMBG results alone for those in Groups 2 & 3 with all participants and healthcare professionals involved in the study blinded to the HbA1c results taken as part of the study visit. The final HbA1c result was reported once the participant completed the study.Results: Of the 446 participants randomised, 259 were male (58%) with mean (range) age 61.7 (27 - 80)years. 267 participants (60%) had diabetes for 5 years or more with 85 (19%) having complications associated with the condition. There were no significant differences in the demographic profiles of the 3 groups. The primary outcome measure was HbA1c at 12 months and the mean (SD) HbA1c at randomisation was 8.6(1.1)%, 8.5(1.1)%, 8.6(1.2)% for Groups 1, 2 & 3 respectively. 323 participants attended the final visit at 12 months when the mean (sd) HbA1c was 8.3(1.31)% (n=116, p