Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 18 |
| Release | : 2015-07-28 |
| ISBN-10 | : 9789264243088 |
| ISBN-13 | : 9264243089 |
| Rating | : 4/5 (089 Downloads) |
Book Synopsis Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes by : OECD
Download or read book Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances. In this test, the used genetic endpoints measure mutation at hypoxanthine-guanine phosphoribosyl transferase (HPRT), and at a transgene of xanthineguanine phosphoribosyl ...