Mechanobiology of Cell-Cell and Cell-Matrix Interactions

Download or read book Mechanobiology of Cell-Cell and Cell-Matrix Interactions written by A. Wagoner Johnson and published by Springer Science & Business Media. This book was released on 2011-02-21 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.