Mechanistic and Synthetic Studies of Asymmetric Reactions Catalyzed by Cinchona Alkaloids
| Author | : Jun Song |
| Publisher | : |
| Total Pages | : 277 |
| Release | : 2007 |
| ISBN-10 | : 1109959494 |
| ISBN-13 | : 9781109959499 |
| Rating | : 4/5 (499 Downloads) |
Book Synopsis Mechanistic and Synthetic Studies of Asymmetric Reactions Catalyzed by Cinchona Alkaloids by : Jun Song
Download or read book Mechanistic and Synthetic Studies of Asymmetric Reactions Catalyzed by Cinchona Alkaloids written by Jun Song and published by . This book was released on 2007 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: We discovered a highly enantioselective Mannich reaction of 1,3-dicarbonyl compounds to N-Boc protected aryl and alkyl imines by using cinchona alkaloid derivatives bearing thiourea functionalities at C9 position. Products of the Mannich reaction are readily transformed into beta-amino acids or beta-amino ketones.