High Altitude Sickness – Solutions from Genomics, Proteomics and Antioxidant Interventions

Download or read book High Altitude Sickness – Solutions from Genomics, Proteomics and Antioxidant Interventions written by Narendra Kumar Sharma and published by Springer Nature. This book was released on 2022-06-30 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the recent advances in the development of proteomics-based biomarkers for the non-invasive diagnosis of altitude sickness and explores the potential of antioxidant therapy for this sickness. The first chapters introduce the associated pathophysiology and provide mechanistic insights into the enhanced generation of reactive oxygen and nitrogen species (RONS), which leads to an increase in oxidative damage to lipids, proteins, and DNA. The book then highlights the current problems relating to the diagnosis and treatment of altitude sickness and summarizes novel approaches for identifying potential biomarkers and therapeutics. Lastly, it explores the therapeutic efficacy of antioxidant agents.