Data Management of Protein Interaction Networks

Download or read book Data Management of Protein Interaction Networks written by Mario Cannataro and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current PPI databases do not offer sophisticated querying interfaces and especially do not integrate existing information about proteins. Current algorithms for PIN analysis use only topological information, while emerging approaches attempt to exploit the biological knowledge related to proteins and kinds of interaction, e.g. protein function, localization, structure, described in Gene Ontology or PDB. The book discusses technologies, standards and databases for, respectively, generating, representing and storing PPI data. It also describes main algorithms and tools for the analysis, comparison and knowledge extraction from PINs. Moreover, some case studies and applications of PINs are also discussed.