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OECD Guidelines for the Testing of Chemicals, Section 4 Guideline No. 497: Defined Approaches on Skin Sensitisation
Language: en
Pages: 53
Authors: OECD
Categories:
Type: BOOK - Published: 2023-07-04 - Publisher: OECD Publishing

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A Defined Approach (DA) consists of a selection of information sources (e.g in silico predictions, in chemico, in vitro data) used in a specific combination, an
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442D: In Vitro Skin Sensitisation Assays addressing the Adverse Outcome Pathway Key Event on Keratinocyte activation
Language: en
Pages: 67
Authors: OECD
Categories:
Type: BOOK - Published: 2018-06-27 - Publisher: OECD Publishing

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This Test Guideline (TG) provides an in vitro procedure (the ARE-Nrf2 luciferase test method) used for supporting the discrimination between skin sensitisers an
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442C: In Chemico Skin Sensitisation Assays addressing the Adverse Outcome Pathway key event on covalent binding to proteins
Language: en
Pages: 63
Authors: OECD
Categories:
Type: BOOK - Published: 2015-02-05 - Publisher: OECD Publishing

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This Test Guideline addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. It provides an in chemico procedure (D
Toxicology for the Health and Pharmaceutical Sciences
Language: en
Pages: 531
Authors: Antonio Peña-Fernández
Categories: Medical
Type: BOOK - Published: 2021-12-21 - Publisher: CRC Press

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There is an increasing need for knowledge of toxicology to safeguard the use of chemicals in industry and in the public and private sectors. The study of toxico
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 442E: In Vitro Skin Sensitisation In Vitro Skin Sensitisation assays addressing the Key Event on activation of dendritic cells on the Adverse Outcome Pathway for Skin Sensitisation
Language: en
Pages: 91
Authors: OECD
Categories:
Type: BOOK - Published: 2024-06-25 - Publisher: OECD Publishing

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The present Key Event based Test Guideline (TG) addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. Skin sensi