Clinical Trials, Second Edition, offers those engaged in clinical trial design a valuable and practical guide. This book takes an integrated approach to incorpo

Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and con

The classic, definitive guide to the design, conduct, and analysis of randomized clinical trials.

This classic reference, now updated with the newest applications and results, addresses the fundamentals of such trials based on sound scientific methodology, s

Successful drug development relies on accurate and efficient clinical trials to deliver the best and most effective pharmaceuticals and clinical care to patient