Apoptosis Methods in Pharmacology and Toxicology

Download or read book Apoptosis Methods in Pharmacology and Toxicology written by Myrtle A. Davis and published by Springer Science & Business Media. This book was released on 2007-10-26 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Myrtle A. Davis has assembled a panel of cutting-edge scientists to describe their best methods for detecting, illuminating, and quantifying apoptotic mechanisms in a way that is useful for the design of toxicology and pharmacology studies. These state-of-the-art techniques include flow cytometric, fluorometric, and laser scanning methods for quantifying and characterizing apoptosis, as well as protocols for the use of DNA microarray technology, high throughput screens, and ELISA. Immunocytochemical methods for measuring biochemical and molecular endpoints in tissue sections will be highly useful for those carrying out studies in whole animal models as opposed to cell culture systems.