Fully updated, this revised edition describes the statistical aspects of both the design and analysis of trials, with particular emphasis on the more recent met

Statistical Design, Monitoring, and Analysis of Clinical Trials, Second Edition concentrates on the biostatistics component of clinical trials. This new edition

Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps

This book explains statistics specifically for a medically literate audience. Readers gain not only an understanding of the basics of medical statistics, but al

More and more frequently, clinical trials include the evaluation of Health-Related Quality of Life (HRQoL), yet many investigators remain unaware of the unique