Decades of research on the tumor suppressor p53 have revealed that it plays a significant role as a "guardian of the genome," protecting cells against genotoxic

All of us have lurking in our DNA a most remarkable gene, which has a crucial job - it protects us from cancer. Known simply as p53, this gene constantly scans

This volume offers a comprehensive review of the functions of the p53 family. The contributors examine the normal roles of these transcription factors, their ev

This work serves as an introduction to the applications of molecular biology in the field of oncology. It provides a basic understanding of the genetic events i

p53 has emerged as a key tumor suppressor and important target for novel cancer therapy. This book, written by world-leading p53 researchers including many of t