Oral antidiabetic drugs and GLP-1 analogues in the treatment of type 2 diabetes

Download or read book Oral antidiabetic drugs and GLP-1 analogues in the treatment of type 2 diabetes written by Sics Editore and published by SICS Editore. This book was released on 2014-10-01 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral medication should be introduced at an early stage. In the absence of contraindications, medication should be started when the HbA1c concentration exceeds 6.5–7.0% (48–53 mmol/mol) despite non-pharmacological intervention. Metformin is the drug of choice. If one antidiabetic drug does not lower the HbA1c value to below 7.0 % (53 mmol/mol), add another and possibly a third antidiabetic drug unless there are contraindications. Insulin therapy must be initiated at the latest when HbA1c remains over 7.0% despite medication with oral antidiabetic drugs or with injectable GLP-1 analogues. A GLP-1 analogue may also be combined with basic insulin treatment.