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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay
Language: en
Pages: 37
Authors: OECD
Categories:
Type: BOOK - Published: 2022-06-30 - Publisher: OECD Publishing

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This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the p
Essentials of Pharmatoxicology in Drug Research, Volume 1
Language: en
Pages: 754
Authors: Rakesh Kumar Tekade
Categories: Medical
Type: BOOK - Published: 2023-03-23 - Publisher: Elsevier

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Toxicity and Toxicodynamics, Volume One in the Essentials of Pharmatoxicology in Drug Research series provides an overview on the essentials of toxicology, risk
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 474: Mammalian Erythrocyte Micronucleus Test
Language: en
Pages: 21
Authors: OECD
Categories:
Type: BOOK - Published: 2016-07-29 - Publisher: OECD Publishing

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The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythro
Test No. 489: In Vivo Mammalian Alkaline Comet Assay
Language: en
Pages: 25
Authors: OECD
Categories:
Type: BOOK - Published: 2014-09-26 - Publisher: OECD Publishing

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The in vivo alkaline single cell gel electrophoresis assay, also called alkaline Comet Assay is a method measuring DNA strand breaks in eukaryotic cells.
Genetic Toxicology
Language: en
Pages: 508
Authors: Albert P. Li
Categories: Medical
Type: BOOK - Published: 1991-03-27 - Publisher: CRC Press

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Genetic Toxicology is a comprehensive book covering the historical perspective of genetic toxicology; basic mechanisms of mutations and chromosomal effects; hea