This book provides the readers with an overview of research on p53, which has been shown to play a role in numerous crucial biological pathways in normal and ca

This book provides the readers with an overview of research on p53, which has been shown to play a role in numerous crucial biological pathways in normal and ca

The current year (2004) marks the Silver Anniversary of the discovery of the p53 tumor suppressor. The emerging ?eld ?rst considered p53 as a viral antigen and

TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are mostly full-length with a single amino acid change and are ab