Epigenetic Targets in Drug Discovery

Download or read book Epigenetic Targets in Drug Discovery written by Wolfgang Sippl and published by Wiley-VCH. This book was released on 2009-08-03 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fueled by the expertise of a team of international specialist authors, this first reference on the booming topic covers everything a drug researcher needs to know about targeting epigenetic mechanisms of disease. The first part of the book surveys current methodologies for finding and validating drug candidates that act via epigenetic mechanisms. The second part systematically surveys known and suspected drug targets within the epigenetic machinery, including the discovery and development of vorinostat, the first marketed epigenetic drug.