Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs
Author | : Rainer H. Müller |
Publisher | : CRC Press |
Total Pages | : 410 |
Release | : 1998 |
ISBN-10 | : 3887630696 |
ISBN-13 | : 9783887630690 |
Rating | : 4/5 (690 Downloads) |
Download or read book Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs written by Rainer H. Müller and published by CRC Press. This book was released on 1998 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore possible new approaches for overcoming poorly soluble drugs - a challenge to drug formulation work and an increasing problem. Many newly developed drugs are poorly soluble, very often simultaneously in aqueous and in organic media. Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs aims to: review the possibilities, limitations and future perspectives of emulsions as drug carriers considering technology from other than the phamaceutical industry (i.e food industry). show the production technology of nanosuspensions, explain the special dissolution properties (i.e. increased saturation solubility) and increased dissolution velocity (theory), and cover the possible applications. present the theory of high pressure homogenization and high pressure extrusion in dispersion techniques, including examples of applications and size measurements in concentrated dispersions.